The use of aspirin at least once per month is associated with a significant decrease in pancreatic cancer risk, according to results of a large case-control study presented at the AACR 102nd Annual Meeting 2011, held here April 2-6. Xiang-Lin Tan, Ph.D., M.D., a research fellow at Mayo Clinic in Rochester, Minn., said the findings [...]
Most breast cancers are fueled by estrogen, and anti-estrogenic agents often work for a time to control the cancers. But many of these cancers become resistant to the drugs for reasons that are not understood, leaving patients with limited treatment options. Now researchers at the Georgetown Lombardi Comprehensive Cancer Center, a part of Georgetown University [...]
Breast cancer screening that includes MRI scans may reduce the chance of finding advanced cancer in women at high genetic risk of the disease, a new study suggests. That’s because MRI appears to discover their breast cancers at an earlier stage. Whether this means women in the high-risk group will live longer isn’t clear yet, [...]
Most women are infected with human papillomavirus (HPV), which can cause cervical cancer – yet few develop the cancer. Now researchers at Georgetown Lombardi Comprehensive Cancer Center, a part of Georgetown University Medical Center, believe they have found the missing link explaining why: activation of the beta-catenin oncogene. At the American Association for Cancer Research [...]
Breast cancer survivors who experience extreme weight gain have an increased risk of death after breast cancer diagnosis. Moderate weight gain did not affect breast cancer outcomes. These study results were presented at the AACR 102nd Annual Meeting 2011, held here April 2-6. The investigation, which looked at the association of post-diagnosis weight gain and [...]
Smoking increases the risk of breast cancer, but the risk differs by obesity status in postmenopausal women, according to data from an analysis of the Women’s Health Initiative observational study. A significant association between smoking and breast cancer risk was observed in non-obese women, but not in obese women. The results were similar regardless of [...]
Protein aggregation, generally associated with Alzheimer’s and mad cow disease, turns out to play a significant role in cancer. In a paper published in Nature Chemical Biology, Frederic Rousseau and Joost Schymkowitz of VIB, K.U.Leuven and Vrije Universiteit Brussel describe that certain mutations of p53, an important tumor suppressor, cause the protein to misfold in [...]